24-hour sustained-release MicroActive® CoQ10 with BioPQQ® to support mitochondrial, cognitive and cardiovascular health | PQQ and CoQ10 promote antioxidant activity and mitochondrial health through different mechanisms, providing multifunctional support for cardiovascular health and neuroprotection. PQQ promotes cardiovascular health by supporting heart muscle function, cellular oxygen utilization and protecting cell membranes from oxidative stress. PQQ maintains neural health by supporting nerve growth factor (NGF) and supporting synaptic and intracellular neuronal responses by maintaining healthy N-methyl D-aspartate (NMDA) receptor activity. The NMDA receptor is the primary conduit for excitatory glutamate neurotransmission and is regarded as an important target for maintaining neuronal health. Mechanistic investigations suggest that PQQ supports several signal transduction pathways that are important in maintaining mitochondrial homeostasis and oxidative metabolism. Recent studies show that PQQ supports mental processing. In a double-blind, placebo-controlled clinical trial conducted in 71 middle-aged individuals, BioPQQ supplementation over a 12 week period supported healthy cognitive performance, specifically high-end mental processing. CoQ10 provides cardiovascular, cognitive and antioxidant support to complement the activity of PQQ. It is offered in this formula as water-soluble, enhanced-absorption, sustained-release MicroActive CoQ10. The patented production process results in CoQ10 with superior absorption compared to solubilized and crystalline CoQ10. What is PQQ? PQQ (pyrroloquinoline quinone) is a novel cofactor with antioxidant and B vitamin-like activity PQQ is a unique neuroprotectant and cardioprotectant PQQ is naturally present in vegetables and in the human body, including breast milk BioPQQ is manufactured in Japan using a patented natural fermentation processWhat are the benefits of PQQ? PQQ promotes cardiovascular health by supporting heart muscle function, cellular oxygen utilization and protecting cell membranes from oxidative stress PQQ maintains neural health by supporting nerve growth factor (NGF), neuronal receptor activity and molecular signals that promote mitochondrial function Recent studies show that PQQ supports mental processingWhat are the features of SR-CoQ10? A water-soluble, nanosized CoQ10 generated using a patented process Clinically studied to show superior absorption compared to solubilized and crystalline CoQ10, with low inter-subject variance 24-hour sustained release prolongs plasma CoQ10 levels and allows for convenient once-daily dosing Provides cardiovascular, cognitive and antioxidant support to complement the activity of PQQSR-CoQ10 with PQQ: A powerful combination for cardiac, neural and cognitive healthPQQ and CoQ10 promote antioxidant activity and mitochondrial health through different mechanisms, providing multifunctional support for cardiovascular health and neuroprotection. In a double-blind, placebo-controlled clinical trial conducted in 71 middle-aged individuals, BioPQQ supplementation over a 12 week period supported healthy cognitive performance, specifically high-end mental processing.Pure Encapsulations: A PQQ PioneerPQQ was first discovered in 1979. Since its discovery, scientists have discovered the many facets of cardioprotection and neuroprotection afforded by PQQ. In 1987, Japanese-based Mitsubishi initiated production of PQQ in limited quantities for research purposes. The launch of BioPQQ is a milestone after decades of research and effort to commercialize PQQ.