Spanish Black Radish is an organic supplement designed to support liver health with daily use, and support toxin elimination with acute use.*
^Ingredients that are not grown on our farm, or if our supply is short, are sourced from certified organic farms.
Standard Process conducted an open-label pilot study to evaluate the efficacy of Spanish black radishes in inducing Phase I and II enzymes in healthy male subjects (n=20). Acetaminophen is metabolized in the liver through pathways that involve Phase II enzymes, including conjugation, sulfation, and glucuronidation, that produce measurable metabolites in blood and urine. Consumption of Spanish black radishes increased liver detoxification capacity and positively altered the metabolism of acetaminophen via increased urinary excretion.4
Spanish black radishes (Raphanus sativus l. var. niger) are particularly rich in a class of phytonutrients called glucosinolates, which have been associated with several beneficial health outcomes attributed to consumption of cruciferous vegetables.1, 2
The main mechanism of action through which metabolites of glucosinolates mediate their beneficial effects may be via the induction of metabolic detoxification Phase I and II enzymes, as well as induction of antioxidant enzymes.1-5
The glucosinolates in Spanish black radishes are unique in both content and concentration in comparison to other cruciferous vegetables.2 For example, the glucosinolates in Spanish black radishes make up over 4% in sprout of their total dry weight; glucosinolates in more common crucifers, such as broccoli, only constitute 1% of the broccoli sprout.2-4 In contrast to more common crucifers, >65% of the glucosinolates present in Spanish black radishes is glucoraphasatin.2 The metabolite of glucoraphasatin, 4-methylthio-3-butenyl isothiocyanate (raphasatin), carries similar potency as sulforaphane (the metabolite of glucoraphanin that is particularly abundant in broccoli) on Phase II gene expression.2,4
Phase I and phase II detoxification enzymes work together to help the body break down and manage compounds that need to be removed. Mice fed a diet containing 20% Spanish black radishes for two weeks showed significant enhancement of the metabolism of toxins as demonstrated by significantly increased expression of Phase I and II detoxification enzymes.5
Radishes (Raphanus sativus L.) are a member of the cruciferous vegetable family that contains broccoli, cauliflower, cabbage, and kale. Radishes are available in varieties that differ in terms of size, shape, and color. Spanish Black Radishes (SBR) (Raphanus sativus l. var. niger) are a variety that is particularly rich in a class of phytonutrients called glucosinolates.
Since 1929, Standard Process has been the visionary leader in whole food nutrient solutions. We apply systems thinking to holistic nutrition that empowers practitioners to transform lives. Dedicated to the whole food philosophy of our founder, Dr. Royal Lee, our goal is to carry on his mission to provide nutrients for the body that are as close as possible to how they are found in nature.
Our products include foods that are prepared in a way that safeguards their nutritional value. The majority of these ingredients are grown locally on our certified organic farm and may require chopping, dicing, juicing and/or drying for use in our products. The resulting whole food ingredients are then added to a formula that may include whole food extracts, animal tissue extracts and concentrates, botanicals, whole food isolates and synthetic ingredients. These highly complex combinations contain a variety of elements designed to trigger trophic effects that support the body’s healthy balance and wellness.*
* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
