SAM-e vegetarian capsules deliver 200 mg of S-adenosyl-methionine in acid-resistant capsules that provide both protection and pH targeted release in intestinal fluid. | SAM-e delivers 200 mg of S-adenosyl-methionine in acid-resistant capsules that provide both protection and pH-targeted release in intestinal fluid. SAM-e is a methyl donor in the methylation reactions shown to form monoamine neurotransmitters such as dopamine, serotonin and norepinephrine. Human studies show SAM-e supports positive mood and healthy central nervous system function.