Active B12 1000 by Seeking Health provides two active "coenzyme" forms of vitamin B12, methylcobalamin and adenosylcobalamin, in a in a lower dose of 1,000 mcg (1 mg) per lozenge. As "coenzyme" forms, methylcobalamin and adenosylcobalamin are the forms required by certain B12-dependent enzymes and reactions within the body. Vitamin B12 is required for proper red blood cell formation, neurological function, and DNA synthesis. Vitamin B12 functions as a cofactor for methionine synthase and L-methylmalonyl-CoA mutase. Methionine synthase catalyzes the conversion of homocysteine to methionine. Methionine is required for the formation of SAMe (S-adenosylmethionine), an important methyl donor.*
Vitamin B12 is naturally present in seafood, shellfish, liver, eggs and dairy products. It may be harder for vegetarians and vegans to meet their daily needs for vitamin B12 from food sources without relying on supplements or fortified foods.*
As each individual may have different needs for vitamin B12, the dose of this vitamin contained in Active B12 1000 may not be ideal for everyone. Working with a qualified healthcare professional is the best way determine the appropriate dose for your individual needs. The lozenges can be broken down into halves or quarters if a lower dose is desired.
For a higher (5,000 mcg) dose of vitamin B12 per lozenge, consider our Active B12 5000. For a similar product without the methylcobalamin, consider our Adeno B12. For vitamin B12 in the form of hydroxocobalamin, consider our Hydroxo B12.